The Itsy Bitsy Spider is an American animated fantasy-comedy television series in the Itsy Bitsy Spider franchise produced by Hyperion Animation. It was broadcast on the USA Network's USA Cartoon Express.
The series revolves around a little girl named Leslie McGroarty who is befriended by a spider named Itsy. The title character's voice was done by Frank Welker.
Itsy is a harmless spider. He is Leslie's best friend. He is the deuteragonist (second most important) of the series. Itsy Bitsy is also the main protagonist of the short film.